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Solving scale-up and solubility challenges in liquid chromatography

 

A new type of liquid chromatography column

Develop your understanding of how HPCCC can help you tackle solubility and scale-up issues in liquid chromatography
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Where to gain the greatest benefit from using the technique

HPCCC instruments are successfully being used in synthetics (small or large molecules), peptides and natural products.
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What is the most suitable product for you?

Our HPCCC instrument range allows you work at any scale of liquid chromatography; analytical chromatography; preparative chromatography; industrial chromatography
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Making the technique work for you

We give an overview, to develop your understanding of instrument installation; method development & optimisation and scale-up.
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Further details about Dynamic Extractions

Our aim is to meet your precise needs. As well as supplying HPCCC instruments, we provide scientific and technical support; perform feasibility studies; purification method development; gram to kilogram separation services.
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Our High Performance Countercurrent Chromatography (HPCCC) instruments have been developed to solve the challenges found in liquid chromatography today, of easy scale-up and improving sample loadings with solutions to solubility problems. The Dynamic Extraction HPCCC products are intended to be used in all circumstances where liquid chromatography techniques, such, as reverse phase HPLC (rp-HPLC) or flash chromatography struggle.

Working with our instruments enables chemists and chromatographers to solve scale-up and solubility problems because they can now use a liquid stationary phase. Working with both liquid mobile and stationary phases offers a greater range of solutions to solubility challenges; however once a purification is developed, it can then be scaled seamlessly from milligram to gram to kilo and beyond. Using HPCCC instruments allows chemists and chromatographers to focus their time developing drugs not liquid chromatography methods.

We primarily work in: drug discovery; drug development and medicinal chemistry. Typical application areas for our products are preparative chromatography and process chromatography; active material purification and isolation; natural products isolation.

Please use this website as a resource to develop your understanding of HPCCC instruments and benefits of using a liquid stationary phase.

 
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