High Performance Counter Current Chromatography (HPCCC) is an innovative, complementary and orthogonal technique to solid phase chromatography methods.
Preparative scale (mg to kg) chromatographers who use either normal or reversed phase, High Performance Liquid Chromatography (HPLC) or flash chromatography should consider using this technique which will fit seamlessly into their workflow and provide productivity improvements in many applications.
In HPCCC, the stationary and mobile phases comprise a pair of selected immiscible liquids. Using liquids for both stationary and mobile phases confers a number of unique features for the preparative scale chromatographer:
- Selectivity driven high resolution purification
- Significantly higher mass throughput
- Simple and reliable scale-up
- Quick post-purification work up
- Greener chromatography
Dynamic Extractions HPCCC instruments (see picture installation page) replaces the conventional, solid-packed column in standard HPLC set ups. High Performance Counter Current Chromatography is readily automated to provide scouting of purification methods in a manner very similar to that used in solid phase chromatographic method scouting.
Dynamic Extractions has expertise and experience in the application of HPCCC instruments within many application areas and can help you successfully integrate the instruments into your purification workflow.
To discover more about how High Performance Counter Current Chromatography instruments could enhance your purification process, follow the links above or contact us.
Read about the key benefits of using liquid stationary phase and our High Performance Counter Current Chromatography Technologies
A new type of liquid chromatography column
Develop your understanding of how high performance counter current chromatography can help you tackle solubility and scale-up issues in liquid chromatographyWhere to gain the greatest benefit from using counter current shomatography
High performance counter current chromatography instruments are successfully being used for the purification of compounds such as synthetic (any size of molecule including peptides), peptides of biological origin and natural products.What is the most suitable chromatography for you?
Our high performance counter current chromatography instrument range allows you work at any scale of chromatography; analytical; preparative; pilot/processMaking the counter current chromatography technique work for you
We give an overview, to develop your understanding of instrument high performance counter current chromatography systems installation; method development & optimisation and scale-up.Further details about Dynamic Extractions
Our aim is to help you to meet your precise chromatographic requirements. As well as supplying high performance counter current chromatography instruments, we provide scientific and technical support; perform feasibility studies; purification method development; gram to kilogram separation services.For more information on our high performance counter current chromatography products and services or to discuss potential applications please contact us or request a quote.
