The range of Chromatography applications to which Dynamic Extractions High Performance CCC (HPCCC) instruments are suited includes those of chemists and chromatographers working in drug discovery; drug development; active material purification; active material isolation and trace amount isolation.
Although this liquid-liquid partition chromatography technique may be successfully applied to the separation of compounds right across the range from small synthetic to naturally occurring macromolecular species, it is particularly attractive in the following circumstances:
- Where the solubility of a sample is poor to the point of limiting throughput in existing Reverse Phase liquid chromatography purifications
- Where you want to quickly purify target compounds from crude samples, which are at an embryonic stage in their chemistry development
- Any application where target compounds are present at a low concentration in crude samples
- Where you do not want to re-develop your purification: as production scale-up proceeds it is often necessary to redevelop solid-liquid chromatographic separations.
By means of enhanced throughput, performance and selectivity, the technique provides additional chromatographic options and opportunities. Contact us to discuss how Dynamic Extractions technology can improve performance and benefit your own particular chromatographic applications.
